Phase I trials of dexrazoxane and other potential applications for the agent. Growth velocity monitoring of the efficacy of different therapeutic protocols in a group of thalassaemic children. Pecoud A, Donzel P, Schelling JL. View abstract. Guldager B, Jorgensen PJ, Grandjean P. Metal excretion and magnesium retention in patients with intermittent claudication treated with intravenous disodium EDTA. J Am Coll Nutr 1982;1:207-14. 2012;7:CD000230. View abstract. A lung disease that makes it harder to breathe (chronic obstructive pulmonary disease or COPD). Grahn BH, Paterson PG, Gottschall-Pass KT, Zhang Z. Zinc and the eye. Taking zinc by mouth does not decrease the risk for upper respiratory tract infections. Med J Australia 1989;15:113. 315-45. Arch Neurol. Czerwinski, A. W., Clark, M. L., Serafetinides, E. A., Perrier, C., and Huber, W. Safety and efficacy of zinc sulfate in geriatric patients. View abstract. Regularly consuming high doses (greater than 100 mg) for extended periods of time may potentially contribute to your risk of prostate cancer. People with Wilson disease have too much copper in their bodies. J Am Coll Nutr 1991;10:372. You do not want to overdo it with zinc. View abstract. Effect of zinc supplementation on clinical course of acute diarrhoea. View abstract. View abstract. Rodriguez de la Serna A, Diaz-Rubio M. Multicenter clinical trial of zinc acexamate in the prevention of nonsteroidal antiinflammatory drug induced gastroenteropathy. Pories, W. J., Henzel, J. H., Rob, C. G., and Strain, W. H. Acceleration of wound healing in man with zinc sulphate given by mouth. A double-blind study. Yousefi A, Khani Khoozani Z, Zakerzadeh Forooshani S, Omrani N, Moini AM, Eskandari Y. Zinc sulfate supplementation for treatment of recurring oral ulcers. Clin Nephrol 1981;16:181-7. Brody I. Topical treatment of recurrent herpes simplex and post-herpetic erythema multiforme with low concentrations of zinc sulphate solution. View abstract. Early research suggests that applying a zinc sulfate solution improves plane warts but not common warts. View abstract. Alterations in calcium, magnesium, iron, and zinc metabolism by dietary cholestyramine. J Wound Care 2005;14(5):233-236. View abstract. Prasad AS, Oberleas D, Lei KY, et al. J Nutr 2001;131:1414-20. is one of the side effects of atenolol a cough? A 50-milligram dose of zinc exceeds the tolerable upper intake level for zinc for every age group, according to the Linus Pauling Institute. Zahiri Sorouri Z, Sadeghi H, Pourmarzi D. The effect of zinc supplementation on pregnancy outcome: a randomized controlled trial. Am J Clin Nutr 2002;76:805-12.. View abstract. Zumkley H, Bertram HP, Vetter H, et al. The effects of thiazides on serum and urinary zinc in patients with renal calculi. Br J Dermatol 1977;97:681-4. Akram M, Sullivan C, Mack G, Buchannan N. What is the clinical significance of reduced manganese and zinc levels in treated epileptic patients? Hill, G. M., Brewer, G. J., Juni, J. E., Prasad, A. S., and Dick, R. D. Treatment of Wilson's disease with zinc. View abstract. Effects of zinc supplementation on endocrine outcomes in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. Patro, B., Szymanski, H., and Szajewska, H. Oral zinc for the treatment of acute gastroenteritis in Polish children: a randomized, double-blind, placebo-controlled trial. Effect of oral contraceptive agents on nutrients: I. Zinc, biochemical markers of nutrition, and type I osteoporosis. Diet and benign prostatic hyperplasia: a study in Greece. View abstract. Applying zinc oxide paste also seems to improve the healing of diaper rash. 2015;31(11-12):1358-61. B., Emokpae, A., Oduwole, A. O., Silva, B. O., Abidoye, R. O., and Renner, J. K. Zinc supplementation in children with acute diarrhoea. A., Musharrafieh, U. M., Tamim, H., and Hamadeh, G. N. Topical zinc oxide vs. salicylic acid-lactic acid combination in the treatment of warts. Am J Clin Nutr 2000;72:1516-22. View abstract. J Rheumatol 1997;24:643-6. Vir SC, Love AH. 2005;84(1):35-38. Valberg LS, Flanagan PR, Chamberlain MJ. Antimicrob Agents Chemother 1987;31:1263-5. Am J Physiol 1993;264:G1037-45. Terrin G, Berni Canani R, Passariello A, Messina F, Conti MG, Caoci S, Smaldore A, Bertino E, De Curtis M. Zinc supplementation reduces morbidity and mortality in very-low-birth-weight preterm neonates: a hospital-based randomized, placebo-controlled trial in an industrialized country. J Natl Cancer Inst 2003;95:1004-7.. View abstract. help if you have any side effects that bother you or do not go away. You may also notice your mouth developing a metallic aftertaste. 2005;24(6):979-987. Int Dent J 1993;43:431-9. Fatemi SH, Calabrese JR. Ophthalmology. View abstract. J.Clin.Periodontol. Zinc-induced copper deficiency in an infant. An eye disease that leads to vision loss in older adults (age-related macular degeneration or AMD). Cochrane Database Syst Rev 2010;(6):CD008563. Am J Clin Nutr 2004;80:715-21. Aliment Pharmacol Ther 1993;7:281-6. 1978;114(12):1776-1778. Liver disease in people who drink alcohol. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. 2016;12:CD005436. Burd GD. Natl Institute of Health, 1996. Taste loss associated with oral captopril treatment. View abstract. J Nutr 2003;133:2973s-7s. View abstract. GlaxoSmithKline (GSK) warns about a potential health risk associated with long-term, excessive use of GSK's zinc-containing denture adhesives Super Polygrip Original, Ultra Fresh and Extra Care. View abstract. View abstract. Am J Clin Nutr 2007;85(5):1293-1300. Sandstrom B, Almgren A, Kivisto B, Cederblad A. Zinc supplementation in young children with acute diarrhea in India. 1991; Roy, S. K., Tomkins, A. M., Mahalanabis, D., Akramuzzaman, S. M., Haider, R., Behrens, R. H., and Fuchs, G. Impact of zinc supplementation on persistent diarrhoea in malnourished Bangladeshi children. Facts and Comparisons, St. Louis, MO. View abstract. Unless your doctor has specifically instructed you to take this dose, you should not take 50-milligram zinc supplements. Taking zinc supplements also appears to decrease the risk for complications and infections related to sickle cell disease. A randomized, placebo controlled trial of oral zinc for chemotherapy-related taste and smell disorders. View abstract. Supplemental zinc lowers measures of iron status in young women with low iron reserves. Taking zinc by mouth together with vitamins does not seem to improve AIDS diarrhea-wasting syndrome. Am J Epidemiol 1996;143:1244-56. Injury to the brain, spine, or nerves (neurological trauma). View abstract. Unless your doctor has specifically instructed you to take this dose, you should not take 50-milligram zinc supplements. View abstract. J Toxicol Clin Toxicol 1999;37:279-92. Zinc is an essential mineral that is needed for reproduction, vision, and immune function in the body, nevertheless, the body doesn’t manufacture zinc on its own, hence, it must come from diet or supplements.. Infections of the kidney, bladder, or urethra (urinary tract infections or UTIs). You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. J.Clin.Periodontol. View abstract. Taking zinc by mouth does not seem to help prevent or treat malaria in undernourished children in developing countries. Uebayashi H, Hatanaka T, Kanemura F, Tonosaki K. Acute anosmia in the mouse: behavioral discrimination among the four basic taste substances. Kondo Y, Yamagata K, Satoh M, et al. Taking zinc might reduce how often they need to go to the bathroom. Patchy hair loss (alopecia areata). But you will need to see how your body responds to smaller doses to check for any reactions or adverse side effects first. Lovell MA, Robertson JD, Teesdale WJ, et al. Br J Clin Pharmacol 1991;31:347. Illness from a Shigella bacteria infection (shigellosis). Clin Neurol Neurosurg. Beneficial effect of polaprezinc on cardiac function post-myocardial infarction: A prospective and randomized clinical trial. Bullous lesions in acrodermatitis enteropathica. Gebreselassie, S. G. and Gashe, F. E. A systematic review of effect of prenatal zinc supplementation on birthweight: meta-analysis of 17 randomized controlled trials. Am J Med Sci 1999;318:392-405. Zinc supplementation might potentiate the effect of vitamin A in restoring night vision in pregnant Nepalese women. J Health Popul.Nutr 2008;26(3):356-365. Am J Clin Nutr 2010;91(6):1634-1641. Am J Clin Nutr 2002;75:181-2. Funct Neurol. View abstract. It is not clear whether zinc dietary supplements can help treat diarrhea in children who get enough zinc… Am J Med Sci 1976;272:285-99. Zinc deficiency in attention-deficit hyperactivity disorder. View abstract. Zinc side effects can become potentially serious if you take doses from 150 to 450 mg a day. Dermatol Surg. View abstract. Zinc Won’t Relieve Your Cold Symptoms. J Neurol Sci 1987;77:137-46. There is evidence that children with ADHD might have lower blood levels of zinc than children without ADHD. Psoriatic arthritis treated with oral zinc sulphate. Infant development. Effectiveness of zinc gluconate glycine lozenges (Cold-Eeze) against the common cold in school-aged subjects: a retrospective chart review. Two randomized controlled trials of zinc gluconate lozenge therapy of experimentally induced rhinovirus colds. Quiz: What Do You Know About Vitamin B12 Deficiency? Zinc deficiency in patients with sickle cell disease. View abstract. View abstract. View abstract. 2012 Feb;105(2):39-40, 42. View abstract. "Product Information. View abstract. Bellamy, P. G., Jhaj, R., Mussett, A. J., Barker, M. L., Klukowska, M., and White, D. J. See Reference 3 and 4) Taking a large amount of chelated zinc may also lower your HDL, or "good," cholesterol level while increasing your LDL, or "bad," cholesterol. Yunice AA, Czerwinski AW, Lindeman RD. Efficacy of spirulina extract plus zinc in patients of chronic arsenic poisoning: a randomized placebo-controlled study. thanks. An acceptable zinc-to-copper ratio is somewhere between 2:1 and 15:1 in favor of zinc. Khatun, U. H. F. Impact of zinc and vitamin A supplementation in malnourished hospitalized children suffering from persistent diarrhoea. Zinc is a trace element that is essential for regulating the immune system. View abstract. Dig Dis Sci 1985;30:477-82.. View abstract. View abstract. Cochrane Database Syst Rev. Sharquie, K. E., Khorsheed, A. A. Zinc supplementation for the prevention of pneumonia in children aged 2 months to 59 months. Drugs 1976;11:45-54.. View abstract. 2010;5(4):e10386. Still, consuming over 40 to 60 mg/day may lead to certain zinc overdose side effects, so speak to your health care professional before increasing your dosage. 7-26-1980;110(30):1138-1145. 2012 Mar;30(1):22-6. View abstract. View abstract. Is topical zinc effective in the treatment of melasma? Dixon JS, Bird HA, Martin MF, et al. Li Z, Li B, Song X, Zhang D. Dietary zinc and iron intake and risk of depression: A meta-analysis. View abstract. However, other early research shows that zinc intake is not linked with the risk of esophageal cancer. Zinc gluconate and the common cold: a controlled clinical study. "took 100mg zinc for cold, thought i was taking 25mg tablets but they were 50. how much zinc for over dose?" Zeng, L. and Zhang, L. Efficacy and safety of zinc supplementation for adults, children and pregnant women with HIV infection: systematic review. J Obstet Gynaecol Res. Available from: URL: http://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/" ([cited 2012]): 2. J Child Psychol Psychiatry 1996;37:225-7.. View abstract. Early research suggests that taking zinc reduces cholesterol but not triglycerides in people with clogged arteries. Diarrhea 3. Effects of oral contraceptive agents on trace element metabolism - a review. Early research shows that taking zinc does not reduce tiredness or improve life quality in people with colorectal cancer receiving chemotherapy. J Diabetes Complications. Early research suggests that taking zinc twice daily for 7 days does not improve jaundice in newborns. 2013 Jun 28;6:CD009415. Barceloux DG. Zinc intake and risk of prostate cancer: Case-control study and meta-analysis. The test is quite variable among subjects [ 60 ]. 1980;13(1):20-25. BMC.Infect.Dis. View abstract. Khattar, J. Available for Android and iOS devices. AIDSinfo. J Pediatr 1999;135:689-97. View abstract. Jafek, B. W., Linschoten, M. R., and Murrow, B. W. Anosmia after intranasal zinc gluconate use. 2010;68(6):323-332. (See Reference 3) High doses may cause dizziness, excessive sweating, unexplained tiredness, headache, fever, chest pain, fainting, chills, vomiting, sores in your mouth or throat, shortness of breath, yellow skin or eyes and an increased risk of infections due to a suppressed immune system. View abstract. Am J Clin Nutr 1981;34:1479-83. View abstract. Effect of folic acid and zinc supplementation in men on semen quality and live birth among couples undergoing infertility treatment: a randomized clinical trial. Zinc might decrease how much antibiotic the body absorbs. Varas Lorenzo, M. J. Zinc acexamate and ranitidine in the short- and mid-term management of gastroduodenal ulcers. J Assist Reprod Genet. Mahajan PM, Jadhav VH, Patki AH, et al. ferrous sulfate, folic acid, ergocalciferol, multivitamin, biotin, ascorbic acid, calcium / vitamin d, Fish Oil, Zinc, thiamine. 2013 Oct;67(10):1056-9. Scholl, T. O., Hediger, M. L., Schall, J. I., Fischer, R. L., and Khoo, C. S. Low zinc intake during pregnancy: its association with preterm and very preterm delivery. 2003;24(1):86-89. CMAJ 2012;184:E551-61. Academic Press, New York, 1976. 2018;126(1):78-83. Research suggests that applying a solution containing zinc to the skin daily for 2 months is less effective than standard skin bleaching treatment for people with brown patches on the face. Adv Ther 1996;13:88-94. Barcia, P. J. Broun ER, Greist A, Tricot G, Hoffman R. Excessive zinc ingestion. Ann NY Acad Sci 1992;669:314-6. A., Sowa-Kucma, M., Zieba, A., Popik, P., Pilc, A., and Nowak, G. Zinc supplementation augments efficacy of imipramine in treatment resistant patients: a double blind, placebo-controlled study. View abstract. 6-15-2010;50(12):1653-1660. View abstract. View abstract. View abstract. Research suggests that taking zinc by mouth daily for 90 days does not improve quality of life or symptoms associated with rosacea. Antioxidant vitamin and mineral supplementation and prostate cancer prevention in the SU.VI.MAX trial. Effect of zinc on the treatment of Plasmodium falciparum malaria in children: a randomized controlled trial. Kaji M, Ito M, Okuno T, et al. Alzheimer's disease, beta-amyloid protein and zinc. 2013 Oct;98(4):960-71. Henkin RI, Foster DM, Aamodt RL, Berman M. Zinc metabolism in adrenal cortical insufficiency: effects of carbohydrate-active steroids. Green, J. A., and Al-Nuaimy, A. View abstract. This can lead to pain, diarrhea and other unpleasant symptoms. Hunt JR. Moving toward a plant-based diet; are iron and zinc at risk? Weimar, V. M., Puhl, S. C., Smith, W. H., and tenBroeke, J. E. Zinc sulfate in acne vulgaris. PhD thesis. Zinc Side Effect #1: Stomach Problems Even those of us with resilient stomachs can encounter some substances that irritate us. Long-term use of oral zinc at dosages of 100 mg or more daily can cause a number of toxic effects, including severe copper deficiency, impaired immunity, heart problems, and anemia. Taking zinc along with EDTA and cisplatin (Platinol-AQ) might increase the effects and side effects of cisplatin (Platinol-AQ). Ophthalmology. View abstract. Cochrane Database Syst Rev. View abstract. Arch Dermatol 1977;113:31-6. View abstract. Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals. Thus, zinc supplements are of interest for people with ADHD. © 2005 - 2019 WebMD LLC. Zinc supplementation as adjunct therapy in children with measles accompanies by pneumonia: a double-blind, randomized controlled trial. View abstract. View abstract. 1996;63(4):514-519. Li P, Xu J, Shi Y, Ye Y, Chen K, Yang J, Wu Y. Research shows that taking a multivitamin syrup containing zinc along with conventional treatment can improve recovery time and reduce diarrhea in undernourished children with food poisoning. View abstract. Randomized, double-blind trial of 220 mg zinc sulfate twice daily in the treatment of rosacea. View abstract. (Accessed: 4/12/2017). Ethambutol and the eye: zinc and copper (letter). McCall JT, Goldstein NP, Randall RV, Gross JB. Interactions with the absorption of tetracyclines. Arnold LE, Votolato NA, Kleykamp D, et al. Febrile seizures are seizures that occur during a fever. Lancet 11-26-2005;366(9500):1862-1867. 2015;30(3):181-5. J Am Coll Nutr 1983;2:157-62. Effects of zinc supplementation on fatigue and quality of life in patients with colorectal cancer. Crofton RW, Gvozdanovic D, Gvozdanovic S, et al. Early research shows that increased zinc intake is not linked to a lower risk of stomach cancer. Anosmia due to inhalational zinc: a case report (abstract). Minerals (especially taken in large doses) can cause side effects such as tooth staining, increased urination, stomach bleeding, uneven heart rate, … 2013 Jun 6;12:74. Interaction of riboflavin with zinc bioavailability. But zinc might help to relive pain in some people with this condition. Dent.Mater.J. J Health Popul.Nutr. Friis, H., Ndhlovu, P., Mduluza, T., Kaondera, K., Sandstrom, B., Michaelsen, K. F., Vennervald, B. J., and Christensen, N. O. Also, most studies that showed benefit used zinc citrate in combination with triclosan, which is not available in the US. It's still not clear if taking zinc along with antioxidant vitamins helps prevent age-related vision loss from becoming advanced in people at low risk. Effect of oral zinc supplements on diaper rash in normal infants. If you consume 100 mg – 500 mg per day, you will experience serious side effects. Zinc 50 mg , 100 Caplets Natures Bounty Zinc 50 mg 100 is rated 5.0 out of 5 by 1 . Roy, S. K., Hossain, M. J., Khatun, W., Chakraborty, B., Chowdhury, S., Begum, A., Mah-e-Muneer, Shafique, S., Khanam, M., and Chowdhury, R. Zinc supplementation in children with cholera in Bangladesh: randomised controlled trial. Epidemiology 2002;13:38-44.. View abstract. HIV/AIDS. View abstract. Brooks, W. A., Santosham, M., Roy, S. K., Faruque, A. S., Wahed, M. A., Nahar, K., Khan, A. I., Khan, A. F., Fuchs, G. J., and Black, R. E. Efficacy of zinc in young infants with acute watery diarrhea. Lerman-Sagie T, Statter M, Szabo G, Lerman P. Effect of valproic acid therapy on zinc metabolism in children with primary epilepsy. View abstract. Randomized, controlled trial of zinc supplementation in malnourished Bangladeshi children with acute diarrhea. Epilepsia 1992;33:555-7. 19. View abstract. Clin Neuropharmacol 1998;21:62. Brook AC, Johnston DG, Ward MK, et al. Acta Paediatr. View abstract. Nail molybdenum and zinc contents in populations with low and moderate incidence of esophageal cancer. View abstract. View abstract. Baltimore, MD: Williams & Wilkins, 1999. J Gastroenterol 2013;48(6):698-705. Int.J.Immunopharmacol. Hu, D., Sreenivasan, P. K., Zhang, Y. P., and De, Vizio W. The effects of a zinc citrate dentifrice on bacteria found on oral surfaces. View abstract. Eur.J Clin Nutr. Taking zinc might also help to lower blood sugar in women who develop diabetes during pregnancy. Grazioso CF, Isalgue M, de Ramirez I, et al. Intranasal zinc and anosmia: the zinc-induced anosmia syndrome. 2015 Jan;122(1):162-9. September 20, 2003. https://app.american-rhinologic.org/programs/2003ARSFallProgram071503.pdf (Accessed 24 November 2003). Zinc supplementation and its effect on taste acuity in children with chronic renal failure. View abstract. View abstract. [Ref], Respiratory side effects have included losing sense of smell in patients who use nasal sprays containing zinc.[Ref]. The most commonly reported side effects of moderate chelated zinc supplementation include an upset stomach, vomiting and nausea. Health Technol.Assess. Taking zinc does not seem to reduce the risk of high blood pressure in pregnancy. View abstract. Dadamio J, Van Tournout M, Teughels W, Dekeyser C, Coucke W, Quirynen M. Efficacy of different mouthrinse formulations in reducing oral malodour: a randomized clinical trial. 2013 May;40(5):505-13. Dietary intake of antioxidants and risk of age-related macular degeneration. View abstract. Dig.Dis.Sci 1991;36(9):1204-1208. 2012 Jun;26(2):111-4. Learn more about Zinc Sulfate (Zinc… 1979;59(4):368-370. Ultrastruct.Pathol. Arch Iran Med. Applies to zinc sulfate: oral capsule, oral tablet, oral tablet extended release. Ophthalmology. Nutritional effects of oral zinc supplementation in cirrhosis. Inorganic zinc and the intestinal absorption of ferrous iron. View abstract. Int Urol Nephrol 1997;29:565-74. Arbabi-kalati F, Arbabi-kalati F, Deghatipour M, Ansari Moghadam A. J Adolesc Health Care 1987;8:400-6. The recommended daily allowance (RDA) of elemental zinc for adult women and men is 8 mg and 11 mg per day, respectively. 2013 Aug;57(8):3640-4. Am.J.Clin.Nutr. The healing of gastric ulcers by zinc sulphate. Arcasoy, A., Cavdar, A., Cin, S., Erten, J., Babacan, E., Gozdasoglu, S., and Akar, N. Effects of zinc supplementation on linear growth in beta-thalassemia (a new approach). 1993;50(10):1007-1008. Clin Nephrol 1982;17:254. 2017 Jan;28(1):4-15. Webb JL. View abstract. Taking zinc alone or along with vitamin A might help treat some, but not all, parasite infections in children in developing countries. QJM 2003;96:35-43. Pediatr Dermatol 1999;16:336-8. View abstract. 2018;10(9). 2012 Aug 2;38:36. Br J Dermatol 1990;122:485-9. View abstract. 2000;62(6):663-669. Taking zinc by mouth or giving zinc intravenously (by IV) helps to restore zinc levels in people who are zinc deficient. You may report side effects to Health Canada at 1-866-234-2345. A mild form of gum disease (gingivitis). Mei, W., Dong, Z. M., Liao, B. L., and Xu, H. B. Med Hypotheses 1985;17:157-65. Does hair zinc predict amphetamine improvement of ADD/hyperactivity? Effects of iron, tin, and copper on zinc absorption in humans. Acta Med Scand. Int Urol Nephrol 1996;28:687-94. J Pediatr.Gastroenterol.Nutr 2006;42(3):300-305. Shils ME, Olson JA, Shike M, Ross AC, eds. Urology 1999;54:284-90. DeCook, C. A. and Hirsch, A. R. Anosmia due to inhalational zinc: a case report (abstract). View abstract. View abstract. Gupta, D. N., Mondal, S. K., Ghosh, S., Rajendran, K., Sur, D., and Manna, B. View abstract. Prasad, A. S. and Cossack, Z. T. Zinc supplementation and growth in sickle cell disease. Early research suggests that zinc levels are lower in people with depression. The effect of Breezy candy on halitosis: a double-blind, controlled, and randomized study. BMC.Med 2009;7:22. Indian J Lepr 1994;66:51-7. View abstract. Lomaestro BM, Bailie GR. Zinc sulfate does not appear to improve lung function in children or adolescents with cystic fibrosis, although it may reduce the need for antibiotics. However, taking zinc supplements regularly is not recommended. Treatment of genital herpes simplex virus in male patients. View abstract. J.Am.Coll.Nutr. Br J Nutr 2008;99(3):667-673. View abstract. Results of a double-blind crossover trial. Am J Clin Nutr 2006;83(6):1401-1410. Studies on the bioavailability of zinc in humans: effects of heme and nonheme iron on the absorption of zinc. View abstract. View abstract. Solecki TJ, Aviv A, Bogden JG. Nausea 5. Biol Psychiatry 1996;40:1308-10. Cataracts. This includes things such as abdominal discomfort, heartburn and indigestion. View abstract. However, zinc does not appear to improve nutrient levels in the body so that the body can function properly. Joint swelling (inflammation) in people with psoriasis. Ophthalmology 1999;106:761-77. View abstract. Recovery following peripheral destruction of olfactory neurons in young and adult mice. View abstract. Br.J.Nutr. View abstract. Am J Ther 2002;9:472-5.. View abstract. Meta-analysis of efficacy of zinc acexamate in peptic ulcer. Enhanced zinc utilization during lactation may reduce maternal and infant zinc depletion. Schisterman EF, Sjaarda LA, Clemons T, et al. View abstract. However, it is important to note that it can potentially cause side effects. Golik A, Zaidenstein R, Dishi V, et al. 1. Taking zinc seems to reduce blood sugar, increase insulin levels, improve the way the body uses insulin, and decrease cholesterol and other fats (lipids) in the blood in people with type 2 diabetes. Zinc intake does not appear to be linked to the risk for developing asthma in children. Early research suggests that taking zinc improves survival rates after 5 years in people with a rare type of advanced nose and throat cancer. Semin Oncol 1998;25:31-6. Eur J Pediatr 1995;154:205-8. 3 4 5 Zinc at a dose of more than 50 mg daily might reduce levels of HDL ("good") cholesterol. Effect of ferrous sulfate and multivitamins with zinc on absorption of ciprofloxacin in normal volunteers. View abstract. Castillo-Duran, C., Rodriguez, A., Venegas, G., Alvarez, P., and Icaza, G. Zinc supplementation and growth of infants born small for gestational age. Clin Pharmacol Ther 1975;17:469-74. Lead, zinc, and copper decorporation during calcium disodium ethylenediamine tetraacetate treatment of lead-poisoned children. View abstract. J Med Assoc.Ga 1989;78(9):621-623. People who consume more zinc as part of their diet seem to have a lower risk of developing age-related vision loss. View abstract. Antoniou LD, Shalhoub RJ, Elliot S. Zinc tolerance tests in chronic aremia. Zinc gluconate contains 14.3% elemental zinc; 10 mg zinc gluconate contains 1.43 mg zinc. Absorption of zinc from wheat products fortified with iron and either zinc sulfate or zinc oxide. Lockitch, G., Puterman, M., Godolphin, W., Sheps, S., Tingle, A. J., and Quigley, G. Infection and immunity in Down syndrome: a trial of long-term low oral doses of zinc. If there is an unusual settling of zinc particles in the spray, then the nose either gets too little zinc, not enough to fight the cold, or too much zinc, sometimes so much that it interferes with the sense of smell. Nutr Neurosci. Strause L, Saltman P, Smith KT, et al. Zinc toxicity. However, it doesn't seem to work as well as applying 2% eosin solution. Arsenic poisoning. Some of the dosage forms listed on this page may not apply to the brand name Zinc 50 mg Pink. Rahman, M. J., Sarker, P., Roy, S. K., Ahmad, S. M., Chisti, J., Azim, T., Mathan, M., Sack, D., Andersson, J., and Raqib, R. Effects of zinc supplementation as adjunct therapy on the systemic immune responses in shigellosis. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. View abstract. Headache 4. 2007;2(6):e541. View abstract. Siwek, M., Dudek, D., Paul, I. Age-Related Macular Degeneration PPP - Updated 2015. www.aao.org/preferred-practice-pattern/age-related-macular-degeneration-ppp-2015. A. V., and Andrade, I. C. Zinc hyaluronate effects on ulcers in diabetic patients [Spanish]. Fischer Walker, C. L., Bhutta, Z. Kingberg WG, Prasad AS, Oberleas D. Zinc deficiency following penicillamine therapy. Polk RE, Healy DP, Sahai J, et al. Iannotti, L. L., Zavaleta, N., Leon, Z., Huasquiche, C., Shankar, A. H., and Caulfield, L. E. Maternal zinc supplementation reduces diarrheal morbidity in peruvian infants. Am J Med Sci 1986;292(6):344-349. However, injecting zinc solutions into lesions does not seem to be more effective than conventional treatments. Jackson, J. L., Peterson, C., and Lesho, E. A meta-analysis of zinc salts lozenges and the common cold. J Am Coll Nutr 2004;23:549S-51S. View abstract. J Am Geriatr Soc 1983;31:790-1. Clin Nephrol. Indian Pediatr. J Trop.Pediatr. View abstract. 2011;(10):CD007368. View abstract. Gibson RS, Yeudall F, Drost N, et al. Yoshida, S., Endo, S., and Tomita, H. A double-blind study of the therapeutic efficacy of zinc gluconate on taste disorder. Dermatology 2004;209(1):46-49. View abstract. J Drugs Dermatol 2005;4(1):73-79. The upper limit you should avoid crossing – and one where side effects start to appear – is around 40 mg or higher. Lancet 7-20-1985;2(8447):157. 5-13-1978;1(6122):1283-1284. Penttila O, Hurme H, Neuvonen PJ. 2015 Jan;122(1):212-5. Lopez de Romana D, Lonnerdal B, Brown KH. Br J Clin Pharmacol. View abstract. View abstract. J Nutr Biochem. Carcamo, C., Hooton, T., Weiss, N. S., Gilman, R., Wener, M. H., Chavez, V., Meneses, R., Echevarria, J., Vidal, M., and Holmes, K. K. Randomized controlled trial of zinc supplementation for persistent diarrhea in adults with HIV-1 infection. Early research suggests that zinc intake is not linked with a reduced risk of developing brain cancer. Control of gingivitis and calculus by a dentifrice containing a zinc salt and triclosan. Although there is early evidence that suggests taking zinc together with biotin might be helpful for hair loss, most studies suggest that zinc is not effective for this condition. Umeta M, West CE, Haidar J, et al. Effects of zinc supplementation on efficacy of antidepressant therapy, inflammatory cytokines, and brain-derived neurotrophic factor in patients with major depression. Watson AR, Stuart A, Wells FE, et al. Rev Esp.Enferm.Dig. View abstract. Zinc is a naturally occurring mineral. 11. View abstract. Toxicology 1984;31:207-16. 9th ed. Dutta, P., Mitra, U., Datta, A., Niyogi, S. K., Dutta, S., Manna, B., Basak, M., Mahapatra, T. S., and Bhattacharya, S. K. 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